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| Position | Player | Injury | Status |
| OT | Jonathan Scott | Hand | Probable |
| DE | Dewayne White | Elbow | Probable |
| DE | Ikaika Alama-Francis | Hamstring | Doubtful |
| LB | Teddy Lehman | Foot | Questionable |
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| Position | Player | Injury | Status |
| RB | Ryan Grant | Ankle | Probable |
| WR | Koren Robinson | Knee | Probable |
| TE | Bubba Franks | Knee | Out |
| OT | Chad Clifton | Knee | Probable |
| OT | Mark Tauscher | Ankle | Probable |
| DT | Johnny Jolly | Shoulder | Out |
| LB | Tracy White | Ankle | Probable |
| CB | Charles Woodson | Hip | Probable |
| CB | Will Blackmon | Foot | Out |
| S | Nick Collins | Knee | Out |
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| Status | Definition | ||
| Probable | 75% chance that the player will play in the game | ||
| Questionable | 50% chance that the player will play in the game | ||
| Doubtful | 25% chance that the player will play in the game | ||
| Out | 0% chance that the player will play in the game | ||