| DETROIT LIONS | |||
| Pos. | Player | Injury | Status |
| QB | Jon Kitna | Back | Doubtful |
| QB | Dan Orlovsky | Ankle | Probable |
| WR | Calvin Johnson | Knee | Questionable |
| WR | Roy Williams | Hip | Questionable |
| OG | Stephen Peterman | Hand | Doubtful |
| TE | Casey FitzSimmons | Elbow | Probable |
| CB | Travis Fisher | Groin | Questionable |
| MINNESOTA VIKINGS | |||
| Pos. | Player | Injury | Status |
| WR | Bernard Berrian | Knee | Questionable |
| WR | Sidney Rice | Knee | Questionable |
| TE | Jim Kleinsasser | Foot | Probable |
| C | John Sullivan | Knee | Probable |
| DE | Ray Edwards | Shoulder | Probable |
| LB | Vinny Ciurciu | Concussion | Probable |
| LB | Erin Henderson | Concussion | Questionable |
| CB | Benny Sapp | Hamstring | Questionable |
| S | Madieu Williams | Neck | Doubtful |
| NFL INJURY REPORT GUIDE | |||
| Status | Definition | ||
| Probable | 75% chance that the player will play in the game | ||
| Questionable | 50% chance that the player will play in the game | ||
| Doubtful | 25% chance that the player will play in the game | ||
| Out | 0% chance that the player will play in the game | ||