| DETROIT LIONS | |||
| Pos. | Player | Injury | Status |
| FB | Jerome Felton | Ankle | Out |
| TE | Casey FitzSimmons | Ribs | Doubtful |
| OG | Damion Cook | Knee | Questionable |
| OG | Andy McCollum | Finger | Questionable |
| DT | Cory Redding | Groin | Questionable |
| DT | Chuck Darby | Calf | Questionable |
| LB | Jordon Dizon | Hamstring | Out |
| S | Dwight Smith | Foot | Out |
| CHICAGO BEARS | |||
| Pos. | Player | Injury | Status |
| WR | Brandon Lloyd | Knee | Questionable |
| WR | Marty Booker | Knee | Probable |
| DT | Tommie Harris | Knee | Probable |
| LB | Hunter Hillenmeyer | Thumb | Questionable |
| CB | Charles Tillman | Shoulder | Probable |
| CB | Nathan Vasher | Wrist | Probable |
| S | Danieal Manning | Hamstring | Questionable |
| NFL INJURY REPORT GUIDE | |||
| Status | Definition | ||
| Probable | 75% chance that the player will play in the game | ||
| Questionable | 50% chance that the player will play in the game | ||
| Doubtful | 25% chance that the player will play in the game | ||
| Out | 0% chance that the player will play in the game | ||