| DETROIT LIONS | |||
| Pos. | Player | Injury | Status |
| QB | Dan Orlovsky | Hand | Out |
| QB | Drew Stanton | Concussion | Questionable |
| RB | Kevin Smith | Ankle | Probable |
| WR | Shaun McDonald | Ankle | Questionable |
| OG | Stephen Peterman | Knee | Probable |
| DE | Dewayne White | Calf | Out |
| DT | Chuck Darby | Calf | Questionable |
| DT | Andre Fluellen | Back | Questionable |
| DT | Cory Redding | Groin | Probable |
| LB | Alex Lewis | Pectoral | Out |
| CB | Keith Smith | Groin | Questionable |
| MINNESOTA VIKINGS | |||
| Pos. | Player | Injury | Status |
| TE | Garrett Mills | Ankle | Questionable |
| OL | Artis Hicks | Elbow | Questionable |
| OT | Bryant McKinnie | Ankle | Probable |
| DE | Brian Robison | Knee | Out |
| DE | Jared Allen | Shoulder | Probable |
| DT | Letroy Guion | Ankle | Probable |
| S | Darren Sharper | Ankle | Probable |
| S | Madieu Williams | Shoulder | Probable |
| NFL INJURY REPORT GUIDE | |||
| Status | Definition | ||
| Probable | 75% chance that the player will play in the game | ||
| Questionable | 50% chance that the player will play in the game | ||
| Doubtful | 25% chance that the player will play in the game | ||
| Out | 0% chance that the player will play in the game | ||