| DETROIT LIONS | |||
| Pos. | Player | Injury | Status |
| QB | Matthew Stafford | Knee | Questionable |
| RB | Maurice Morris | Hip | Questionable |
| FB | Jerome Felton | Shoulder | Questionable |
| WR | Calvin Johnson | Knee | Questionable |
| TE | Casey FitzSimmons | Thigh | Questionable |
| TE | Brandon Pettigrew | Hamstring | Probable |
| OT | Gosder Cherilus | Shoulder | Probable |
| DE | Jason Hunter | Ankle | Doubtful |
| DE | Dewayne White | Hamstring | Questionable |
| DT | Grady Jackson | Knee | Probable |
| DT | Sammie Hill | Ankle | Doubtful |
| LB | Jordon Dizon | Foot | Probable |
| LB | Ernie Sims | Shoulder | Probable |
| S | Ko Simpson | Hamstring | Doubtful |
| GREEN BAY PACKERS | |||
| Pos. | Player | Injury | Status |
| RB | DeShawn Wynn | Knee | Out |
| RB | Korey Hall | Calf | Out |
| RB | Brandon Jackson | Ankle | Probable |
| OT | Mark Tauscher | Knee | Out |
| OT | Chad Clifton | Ankle | Probable |
| OG | Daryn Colledge | Knee | Probable |
| C | Jason Spitz | Back | Questionable |
| C | Scott Wells | Hamstring | Questionable |
| DE | Cullen Jenkins | Ankle | Probable |
| DT | Ryan Pickett | Hip | Probable |
| LB | Brady Poppinga | Illness | Probable |
| LB | Jeremy Thompson | Knee | Probable |
| S | Atari Bigby | Knee | Probable |
| NFL INJURY REPORT GUIDE | |||
| Status | Definition | ||
| Probable | 75% chance that the player will play in the game | ||
| Questionable | 50% chance that the player will play in the game | ||
| Doubtful | 25% chance that the player will play in the game | ||
| Out | 0% chance that the player will play in the game | ||